Latest Publications
Selective Targeting of Plasmodium falciparum Hsp90 Disrupts the 26S Proteasome
Mansfield, C.R., Quan, B., Chirgwin, M.E., Eduful, B., Hughes, P.F., Neveu, G., Sylvester, K., Ryan, D.H., Kafsack, B.F.C., Haystead, T.A.J., Leahy, J.W., Fitzgerald, M.C., Derbyshire, E.R. Selective Targeting of Plasmodium falciparum Hsp90 Disrupts the 26S Proteasome. Cell Chemical Biology 2024, 31, 729-742.
Keeler, A.M., D'Ambrosio, H.K., Ganley, J.G., Derbyshire, E.R. Characterization of Unexpected Self-Acylation Activity of Acyl Carrier Proteins in a Modular Type I Apicomplexan Polyketide Synthase. ACS Chemical Biology 2023, 18, 785-793.
Ong, H.W., de Silva, C., Avalani, K., Kwarcinski, F., Mansfield, C.R., Chirgwin, M., Truong, A., Derbyshire, E.R.,** Zutshi, R.,** Drewry, D.** Characterization of 2,4-dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9 and PfPKB. ACS Medicinal Chemistry Letters 2023, 14, 1774-1784.